SCHEMBL894657

SCHEMBL894657

O=C=Nc1ccc(-c2cccc(N=C=O)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.47
MAPK1 P28482 1/20 0.47
CYP3A4 P08684 5/20 0.45
TSHR P16473 1/20 0.45
TRPA1 O75762 1/20 0.44
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
CYP1A2 P05177 1/20 0.38
HSD17B1 P14061 2/20 0.35
HSD17B2 P37059 2/20 0.35
CYP2C9 P11712 1/20 0.35
MEN1 O00255 1/20 0.35
ESR1 P03372 1/20 0.35
KMT2A Q03164 1/20 0.35
CA12 O43570 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
TRIM24 O15164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30365208 0.92 TDP1 (0.48) TDP1MAPK1CYP3A4TSHRTRPA1
SCHEMBL894324 0.92 TDP1 (0.48) TDP1MAPK1CYP3A4TSHRTRPA1
SCHEMBL1899306 0.90 MAPK1 (0.44) TDP1MAPK1CYP3A4TSHRTRPA1
SCHEMBL29849714 0.87 AGXT (0.40) TDP1MAPK1CYP3A4TRPA1ALDH1A1
SCHEMBL29849567 0.87 AGXT (0.40) TDP1MAPK1CYP3A4TRPA1ALDH1A1
SCHEMBL2405824 0.83 CYP3A4 (0.44) TDP1MAPK1CYP3A4TSHRTRPA1
SCHEMBL21993321 0.83 CYP3A4 (0.52) TDP1MAPK1CYP3A4TSHRTRPA1
SCHEMBL139997 0.83 CYP3A4 (0.52) TDP1MAPK1CYP3A4TSHRTRPA1
SCHEMBL29849688 0.83 KIF11 (0.48)
SCHEMBL23721668 0.82 CYP3A4 (0.61) TDP1MAPK1CYP3A4TSHRTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240332628-A1 Silicon-Based Energy Storage Devices With Electrolyte Containing Cyanate Based Compounds ENEVATE CORP (US) 2024-10-03 US claimed
US-20210249689-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ELECTROLYTE CONTAINING CYANATE BASED COMPOUNDS ENEVATE CORPORATION 2021-08-12 US claimed
WO-2021158366-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ELECTROLYTE CONTAINING CYANATE BASED COMPOUNDS ENEVATE CORPORATION (US) 2021-08-12 WO claimed
EP-0024665-B1 DIISOCYANATES OR MIXTURES OF DIISOCYANATES OF THE DIPHENYL-METHANE SERIES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS A SYNTHESIS COMPONENT TO PRODUCE POLYURETHANE PLASTICS ACCORDING TO THE ISOCYANATE-POLYADDITION PROCESS BAYER AG (DE) 1982-05-05 EP claimed
US-20240332628-A1 Silicon-Based Energy Storage Devices With Electrolyte Containing Cyanate Based Compounds ENEVATE CORP (US) 2024-10-03 US disclosed
WO-2024111181-A1 THERMOSETTING RESIN COMPOSITION AND CURED PRODUCT ポリプラ・エボニック株式会社 2024-05-30 WO disclosed
US-11988981-B2 Endless belt, transfer device, and image forming apparatus FUJIFILM BUSINESS INNOVATION CORP. (JP) 2024-05-21 US disclosed
US-20240152077-A1 INTERMEDIATE TRANSFER BELT, TRANSFER DEVICE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2024-05-09 US disclosed
CN-117930606-A Intermediate transfer belt, transfer device, and image forming apparatus 富士胶片商业创新有限公司 2024-04-26 CN disclosed
US-11966175-B2 Intermediate transfer belt cleaning system, transfer device, and image forming apparatus FUJIFILM BUSINESS INNOVATION CORP. (JP) 2024-04-23 US disclosed
US-11960231-B2 Transfer device and image forming apparatus FUJIFILM BUSINESS INNOVATION CORP. (JP) 2024-04-16 US disclosed
US-20240118646-A1 ENDLESS BELT, TRANSFER DEVICE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2024-04-11 US disclosed
EP-1011107-B1 Insulated wire SUMITOMO ELECTRIC WINTEC INC (JP) 2004-09-22 EP disclosed
WO-2004063268-A1 STABILIZATION OF THERMOPLASTIC NANOCOMPOSITES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-07-29 WO disclosed
US-6436537-B1 INSULATED WIRES WITH POLYAMIDEIMIDE COPOLYMERS THE FURUKAWA ELECTRIC CO., LTD. (JP) 2002-08-20 US disclosed
US-6288342-B1 Insulated wire SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 2001-09-11 US disclosed
EP-1011107-A1 Insulated wire Sumitomo Electric Industries, Ltd. (JP) 2000-06-21 EP disclosed
EP-0977209-A1 INSULATED WIRE THE FURUKAWA ELECTRIC CO., LTD. (JP) 2000-02-02 EP disclosed
EP-0543409-B1 Insulated wire SUMITOMO ELECTRIC INDUSTRIES (JP) 1996-07-17 EP disclosed
US-5356708-A Conductor and insulating coating made from polyamideimide base coating SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1994-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240332628-A1 Silicon-Based Energy Storage Devices With Electrolyte Containing Cyanate Based Compounds SIRT3, SLC6A12, HCN2 TDP1 2455/4885MAPK1 579/4885CYP3A4 4039/4885
US-20210249689-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH ELECTROLYTE CONTAINING CYANATE BASED COMPOUNDS SIRT3, SLC6A12, HCN2 TDP1 2455/4885MAPK1 579/4885CYP3A4 4039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.