Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946714 | 0.95 | LMNA (0.43) | KMT2ALMNAL3MBTL1NPSR1 | |
| SCHEMBL8946420 | 0.87 | L3MBTL1 (0.47) | PYGLCXCL8L3MBTL1 | |
| SCHEMBL8946710 | 0.83 | HTT (0.47) | KMT2ALMNAMAPK1LCKL3MBTL1 | |
| SCHEMBL8946618 | 0.80 | L3MBTL1 (0.51) | KMT2ALMNAL3MBTL1 | |
| SCHEMBL8946825 | 0.79 | DHODH (0.41) | KMT2AMAPK1L3MBTL1 | |
| SCHEMBL8946617 | 0.78 | L3MBTL1 (0.53) | PYGLL3MBTL1 | |
| SCHEMBL8952284 | 0.77 | KDR (0.44) | KDRKMT2ALMNAMAPK1L3MBTL1 | |
| SCHEMBL8946535 | 0.76 | SMN1; SMN2 (0.47) | KMT2AMAPK1MEN1 | |
| SCHEMBL8946406 | 0.76 | LPAR1 (0.47) | KMT2ALMNA | |
| SCHEMBL8823125 | 0.75 | NTRK1 (0.39) | KMT2ALMNAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7101940-A | — | — | None | — | — | JP | disclosed |
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| JP-H07101940-A | PYRIMIDINE AND PYRIDINE DERIVATIVES AND PRODUCTION AND USE THEREOF | NIPPON NOHYAKU CO LTD | 1995-04-18 | — | — | JP | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |