Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SLC9A3 | P48764 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946434 | 0.82 | HSD17B3 (0.44) | L3MBTL1ALDH1A1CREBBPMAPTBRD4 | |
| SCHEMBL8946435 | 0.78 | MAPT (0.47) | KDM4EALDH1A1HTR2CHTR2BNPC1 | |
| SCHEMBL8946786 | 0.77 | CREBBP (0.40) | L3MBTL1ALDH1A1CYP1A2CREBBPMAPT | |
| SCHEMBL10438249 | 0.68 | GRIN2D (0.55) | KDM4EL3MBTL1ALDH1A1HTR2CHTR2B | |
| SCHEMBL15383120 | 0.67 | NOTUM (0.40) | KDM4EALDH1A1CREBBPBRD4SMN1; SMN2 | |
| SCHEMBL21371548 | 0.67 | NOTUM (0.40) | KDM4EALDH1A1CREBBPBRD4SMN1; SMN2 | |
| SCHEMBL6949098 | 0.66 | MAOA (0.56) | KDM4EL3MBTL1ALDH1A1MAOANPC1 | |
| SCHEMBL8946692 | 0.65 | HSD17B3 (0.39) | KDM4EALDH1A1CREBBPMAPTBRD4 | |
| SCHEMBL8946697 | 0.65 | HSD17B3 (0.39) | KDM4EALDH1A1CREBBPMAPTBRD4 | |
| SCHEMBL8946705 | 0.65 | HSD17B3 (0.39) | KDM4EALDH1A1CREBBPMAPTBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | disclosed |