Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946595 | 0.87 | L3MBTL1 (0.50) | L3MBTL1CNR1LMNAMEN1KMT2A | |
| SCHEMBL8946857 | 0.85 | L3MBTL1 (0.53) | L3MBTL1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL8946307 | 0.85 | L3MBTL1 (0.50) | L3MBTL1CNR1LMNAMEN1KMT2A | |
| SCHEMBL8946617 | 0.85 | L3MBTL1 (0.53) | L3MBTL1NTRK1 | |
| SCHEMBL8946920 | 0.85 | L3MBTL1 (0.50) | L3MBTL1LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL8946858 | 0.85 | ADORA3 (0.53) | L3MBTL1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL8946547 | 0.85 | L3MBTL1 (0.49) | L3MBTL1MEN1KMT2AALDH1A1NTRK1 | |
| SCHEMBL8946735 | 0.84 | L3MBTL1 (0.51) | L3MBTL1NTRK1MAPTPOLBNPC1 | |
| SCHEMBL8946873 | 0.84 | L3MBTL1 (0.51) | L3MBTL1CNR1LMNAMEN1KMT2A | |
| SCHEMBL8946750 | 0.84 | L3MBTL1 (0.48) | L3MBTL1LMNAMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |