Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946654 | 0.87 | L3MBTL1 (0.55) | L3MBTL1NTRK1NPSR1MAPTRAB9A | |
| SCHEMBL8946735 | 0.85 | L3MBTL1 (0.51) | L3MBTL1NTRK1MAPTRAB9ANPC1 | |
| SCHEMBL8946728 | 0.85 | L3MBTL1 (0.51) | L3MBTL1NTRK1RAB9ACYP2C9DHODH | |
| SCHEMBL8946617 | 0.85 | L3MBTL1 (0.53) | L3MBTL1NTRK1 | |
| SCHEMBL8946885 | 0.81 | DHODH (0.49) | L3MBTL1NTRK1DHODH | |
| SCHEMBL8946873 | 0.81 | L3MBTL1 (0.51) | L3MBTL1NTRK1LMNACYP1A2CYP2C9 | |
| SCHEMBL8946857 | 0.81 | L3MBTL1 (0.53) | L3MBTL1NTRK1MAPTRAB9ANPC1 | |
| SCHEMBL8946420 | 0.80 | L3MBTL1 (0.47) | L3MBTL1NTRK1 | |
| SCHEMBL8946858 | 0.80 | ADORA3 (0.53) | L3MBTL1NTRK1NPSR1MAPTRAB9A | |
| SCHEMBL8946504 | 0.79 | L3MBTL1 (0.47) | L3MBTL1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |