Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946478 | 0.70 | MAPT (0.35) | MAPTMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL8946486 | 0.70 | MAPT (0.35) | MAPTMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL8946494 | 0.70 | MAPT (0.35) | MAPTMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL3034512 | 0.60 | CYP3A4 (0.39) | MAPTMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL8946380 | 0.58 | MAOA (0.34) | MAPTMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL8946284 | 0.57 | HTR2A (0.39) | MAPTMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL15319460 | 0.57 | MAOA (0.35) | ALDH1A1HPGDMAOA | |
| SCHEMBL15319269 | 0.55 | CYP2C19 (0.33) | ALDH1A1KMT2AHPGDHTR2A | |
| SCHEMBL2955343 | 0.54 | ALDH1A1 (0.56) | ALDH1A1HPGD | |
| SCHEMBL9748717 | 0.54 | ACHE (0.50) | MEN1ALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | disclosed |