SCHEMBL9748717

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12326180	0.82	CA1 (0.50)	ACHECYP3A4CYP1A1CYP1A2CYP2E1
	SCHEMBL12989512	0.80	MAPK1 (0.48)	ACHECYP3A4CYP1A1CYP1A2CYP2E1
	SCHEMBL12989388	0.78	CYP11B1 (0.52)	CYP3A4CYP1A2CYP2D6CYP2A6CYP2C9
	SCHEMBL25251070	0.76	LMNA (0.46)	CYP3A4CYP1A2CYP2A6CYP2C19MEN1
	SCHEMBL28492019	0.76	GPR3 (0.46)	ACHECYP3A4CYP1A1CYP1A2CYP2E1
	SCHEMBL1673424	0.76	ALDH1A1 (0.46)	CYP3A4CYP1A1CYP1A2CYP2E1CYP2C8
	SCHEMBL17178230	0.76	CYP1A2 (0.48)	ACHECYP3A4CYP1A1CYP1A2CYP2E1
	SCHEMBL7699015	0.75	MAPT (0.46)	CYP3A4CYP1A2CYP2D6CYP2A6CYP2C9
	SCHEMBL30159166	0.74	ABL1 (0.56)	ACHECYP3A4CYP1A1CYP1A2CYP2E1
	SCHEMBL21114228	0.73	MAPK1 (0.46)	ACHECYP3A4CYP1A1CYP1A2CYP2E1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.