Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 7/20 | 0.52 |
| ▸ | ACACA | Q13085 | 5/20 | 0.52 |
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9998002 | 0.83 | THRB (0.52) | THRBALDH1A1KMT2AMEN1 | |
| SCHEMBL8621115 | 0.77 | THRB (0.50) | ACACBACACATHRBALDH1A1PPARG | |
| SCHEMBL29034768 | 0.77 | MAPT (0.44) | ACACBALDH1A1FFAR1KMT2AMEN1 | |
| 1'-Acetoxychavicol Acetate SCHEMBL17454871 | 0.77 | LMNA (0.47) | ALDH1A1KMT2AMEN1 | |
| 1'-Acetoxychavicol Acetate SCHEMBL3673490 | 0.77 | LMNA (0.47) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL8947205 | 0.75 | LMNA (0.46) | ACACBACACAALDH1A1PPARGPPARA | |
| SCHEMBL18910940 | 0.72 | ACACB (0.49) | ACACBACACATHRBALDH1A1PPARG | |
| SCHEMBL29034776 | 0.72 | TPMT (0.35) | ACACBALDH1A1 | |
| SCHEMBL27628648 | 0.72 | CYP1A2 (0.44) | ALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL61038 | 0.72 | CYP3A4 (0.50) | ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567841-A | ANTICHOLESTEROL AGENT | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-10-22 | — | — | US | disclosed |