SCHEMBL29034776

SCHEMBL29034776

C=CC(OC(C)=O)c1ccc(I)cc1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TPMT P51580 1/20 0.35
ACACB O00763 1/20 0.34
CYP3A4 P08684 2/20 0.33
ALDH1A1 P00352 1/20 0.33
GSK3B P49841 1/20 0.32
SLC6A3 Q01959 1/20 0.31
CCR3 P51677 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
TSHR P16473 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27628648 0.83 CYP1A2 (0.44) CYP3A4ALDH1A1TSHRMAPT
SCHEMBL61038 0.82 CYP3A4 (0.50) CYP3A4ALDH1A1TSHRKDM4EMAPT
SCHEMBL29034768 0.81 MAPT (0.44) ACACBCYP3A4ALDH1A1CA1CA2
1'-Acetoxychavicol Acetate SCHEMBL3673490 0.81 LMNA (0.47) CYP3A4ALDH1A1SLC6A3TSHRKDM4E
SCHEMBL9472147 0.81 CYP3A4 (0.46) CYP3A4ALDH1A1TSHRKDM4EMAPT
1'-Acetoxychavicol Acetate SCHEMBL17454871 0.81 LMNA (0.47) CYP3A4ALDH1A1SLC6A3TSHRKDM4E
SCHEMBL9642843 0.80 PTGS2 (0.46) ACACBCYP3A4ALDH1A1MAPT
SCHEMBL5638474 0.79 ALDH1A1 (0.45) CYP3A4ALDH1A1CA1CA2TSHR
SCHEMBL8947205 0.76 LMNA (0.46) ACACBCYP3A4ALDH1A1TSHR
SCHEMBL7948698 0.76 CYP3A4 (0.44) CYP3A4ALDH1A1TSHRKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116396185-B Preparation method of N-allyl aryl hydrazine compound 江西师范大学 2023-08-18 CN disclosed
CN-116396185-A Preparation method of N-allyl aryl hydrazine compound 江西师范大学 2023-07-07 CN disclosed