Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | CFD | P00746 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61038 | 0.86 | CYP3A4 (0.50) | LMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL9642843 | 0.83 | PTGS2 (0.46) | ACACBACACAALDH1A1CYP3A4MMP12 | |
| SCHEMBL9472147 | 0.81 | CYP3A4 (0.46) | LMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL7948698 | 0.79 | CYP3A4 (0.44) | LMNAALDH1A1SRD5A2CYP3A4TSHR | |
| SCHEMBL29034776 | 0.76 | TPMT (0.35) | ACACBALDH1A1CYP3A4TSHR | |
| SCHEMBL27628648 | 0.76 | CYP1A2 (0.44) | LMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL29034768 | 0.75 | MAPT (0.44) | LMNAACACBALDH1A1CYP3A4 | |
| 1'-Acetoxychavicol Acetate SCHEMBL17454871 | 0.75 | LMNA (0.47) | LMNAALDH1A1CYP3A4TSHR | |
| 1'-Acetoxychavicol Acetate SCHEMBL3673490 | 0.75 | LMNA (0.47) | LMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL8947004 | 0.75 | ACACB (0.52) | ACACBACACAALDH1A1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567841-A | ANTICHOLESTEROL AGENT | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-10-22 | — | — | US | disclosed |