Pyrene

Pyrene

SCHEMBL8947557

O=S(=O)([O-])C(F)(F)F.[Fe+]C1=CC=CC1.c1cc2ccc3cccc4ccc(c1)c2c34

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.33
KCNH2 Q12809 7/20 0.33
ACHE P22303 5/20 0.33
ALDH1A1 P00352 1/20 0.31
CYP1A1 P04798 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
CYP1B1 Q16678 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL8947602 0.92 GPR3 (0.32) GPR3KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL8947526 0.86 GPR3 (0.34) GPR3KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL8947570 0.83 ALDH1A1 (0.42) GPR3KCNH2ALDH1A1CYP1A2HPGD
P-Xylene SCHEMBL8947555 0.82 GPR3 (0.38) GPR3KCNH2ACHEALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL7601538 0.81 GPR3 (0.39) GPR3KCNH2ACHETSHR
Dibenzofuran SCHEMBL8947563 0.78 SMN1; SMN2 (0.36) GPR3ALDH1A1CYP1A2CYP3A4HPGD
Isopropylbenzene SCHEMBL8947643 0.78 GPR3 (0.35) GPR3ALDH1A1
Fluorene SCHEMBL8947571 0.78 GPR3 (0.41) GPR3KCNH2ALDH1A1CYP1A2HPGD
Anisole SCHEMBL8947547 0.78 KCNH2 (0.39) GPR3KCNH2ACHEALDH1A1
O-Xylene SCHEMBL1315098 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5565500-A CURED PRODUCT OBTAINED BY HEATING MIXTURE OF EPOXY RESIN, VINYL ETHER OR VINYL ESTER, IRON-CONTAINING METALLOCENE CIBA-GEIGY CORPORATION (US) 1996-10-15 US disclosed
US-5371259-A Photoinitiators CIBA-GEIGY CORPORATION (US) 1994-12-06 US disclosed
US-4957946-A FERROCENE TYPE COMPLEXES, EPOXY RESINS, VINYL ETHERS AND VINYL ESTERS CIGA-GEIGY CORPORATION (US) 1990-09-18 US disclosed