Dibenzofuran

Dibenzofuran

SCHEMBL8947563

O=S(=O)([O-])C(F)(F)F.[Fe+]C1=CC=CC1.c1ccc2c(c1)oc1ccccc12

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.36
TSHR P16473 3/20 0.35
ALDH1A1 P00352 4/20 0.35
HPGD P15428 4/20 0.35
HTT P42858 4/20 0.35
GAA P10253 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
GPR3 P46089 2/20 0.35
MAPT P10636 6/20 0.34
MAOA P21397 3/20 0.34
KDM4E B2RXH2 2/20 0.34
HSD17B10 Q99714 2/20 0.34
GLA P06280 1/20 0.34
CYP3A4 P08684 1/20 0.34
PGAM1 P18669 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
CDC14B O60729 1/20 0.33
CDC14A Q9UNH5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL8947526 0.84 GPR3 (0.34) GPR3
Trifluoromethanesulfonic Acid SCHEMBL7601538 0.82 GPR3 (0.39) SMN1; SMN2TSHRHTTGAAGPR3
Trifluoromethanesulfonic Acid SCHEMBL8947602 0.81 GPR3 (0.32) GPR3
Trifluoromethanesulfonic Acid SCHEMBL8947570 0.81 ALDH1A1 (0.42) ALDH1A1HPGDCYP1A2GPR3HSD17B10
P-Xylene SCHEMBL8947555 0.80 GPR3 (0.38) SMN1; SMN2ALDH1A1HTTGAAGPR3
Anisole SCHEMBL8947547 0.78 KCNH2 (0.39) ALDH1A1GAAGPR3KMT2AMMP13
Isopropylbenzene SCHEMBL8947643 0.78 GPR3 (0.35) ALDH1A1HTTGPR3MAPTKMT2A
Fluorene SCHEMBL8947571 0.78 GPR3 (0.41) SMN1; SMN2TSHRALDH1A1HPGDHTT
Pyrene SCHEMBL8947557 0.78 GPR3 (0.33) TSHRALDH1A1HPGDCYP1A2GPR3
O-Xylene SCHEMBL1315098 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5565500-A CURED PRODUCT OBTAINED BY HEATING MIXTURE OF EPOXY RESIN, VINYL ETHER OR VINYL ESTER, IRON-CONTAINING METALLOCENE CIBA-GEIGY CORPORATION (US) 1996-10-15 US disclosed
US-5371259-A Photoinitiators CIBA-GEIGY CORPORATION (US) 1994-12-06 US disclosed
US-4957946-A FERROCENE TYPE COMPLEXES, EPOXY RESINS, VINYL ETHERS AND VINYL ESTERS CIGA-GEIGY CORPORATION (US) 1990-09-18 US disclosed