Fluorene

Fluorene

SCHEMBL8947571

O=S(=O)([O-])C(F)(F)F.[Fe+]C1=CC=CC1.c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.41
MAOA P21397 2/20 0.38
ALDH1A1 P00352 5/20 0.34
MAPT P10636 5/20 0.34
SMN1; SMN2 Q16637 4/20 0.34
HPGD P15428 3/20 0.34
HSD17B10 Q99714 2/20 0.34
SRD5A2 P31213 1/20 0.33
BCHE P06276 1/20 0.33
CES1 P23141 1/20 0.33
PDPK1 O15530 1/20 0.32
PTGS2 P35354 2/20 0.32
KCNH2 Q12809 1/20 0.32
KDM4E B2RXH2 5/20 0.32
LMNA P02545 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
GAA P10253 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL8947526 0.84 GPR3 (0.34) GPR3KCNH2
Trifluoromethanesulfonic Acid SCHEMBL7601538 0.82 GPR3 (0.39) GPR3SMN1; SMN2KCNH2LMNANPSR1
P-Xylene SCHEMBL8947555 0.80 GPR3 (0.38) GPR3ALDH1A1SMN1; SMN2BCHEKCNH2
Isopropylbenzene SCHEMBL8947643 0.78 GPR3 (0.35) GPR3ALDH1A1MAPTNPSR1KMT2A
Anisole SCHEMBL8947547 0.78 KCNH2 (0.39) GPR3ALDH1A1KCNH2GAAKMT2A
Dibenzofuran SCHEMBL8947563 0.78 SMN1; SMN2 (0.36) GPR3MAOAALDH1A1MAPTSMN1; SMN2
Pyrene SCHEMBL8947557 0.78 GPR3 (0.33) GPR3ALDH1A1HPGDHSD17B10KCNH2
Trifluoromethanesulfonic Acid SCHEMBL8947602 0.76 GPR3 (0.32) GPR3KCNH2
Trifluoromethanesulfonic Acid SCHEMBL8947570 0.75 ALDH1A1 (0.42) GPR3ALDH1A1HPGDHSD17B10PTGS2
O-Xylene SCHEMBL1315098 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5565500-A CURED PRODUCT OBTAINED BY HEATING MIXTURE OF EPOXY RESIN, VINYL ETHER OR VINYL ESTER, IRON-CONTAINING METALLOCENE CIBA-GEIGY CORPORATION (US) 1996-10-15 US disclosed
US-5371259-A Photoinitiators CIBA-GEIGY CORPORATION (US) 1994-12-06 US disclosed
US-4957946-A FERROCENE TYPE COMPLEXES, EPOXY RESINS, VINYL ETHERS AND VINYL ESTERS CIGA-GEIGY CORPORATION (US) 1990-09-18 US disclosed