Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8158782 | 0.80 | RECQL (0.46) | ALDH1A1L3MBTL1HPGDMAPTKDM4E | |
| SCHEMBL9826049 | 0.77 | MAOB (0.51) | ALDH1A1MAPTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL5383838 | 0.77 | LOXL2 (0.42) | ALDH1A1L3MBTL1MAPTKDM4EHSD17B10 | |
| SCHEMBL10823736 | 0.75 | NPC1 (0.54) | ALDH1A1HPGDKDM4EHSD17B10TP53 | |
| SCHEMBL9826458 | 0.74 | HDAC3 (0.52) | ALDH1A1L3MBTL1MAPTKDM4EHSD17B10 | |
| SCHEMBL11869069 | 0.74 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL7699924 | 0.74 | FLT3 (0.48) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL1062947 | 0.73 | HPGD (0.54) | ALDH1A1HPGDHSD17B10HTTTP53 | |
| SCHEMBL424398 | 0.73 | HDAC3 (0.48) | ALDH1A1L3MBTL1MAPTKDM4EHSD17B10 | |
| SCHEMBL3865052 | 0.73 | TAS1R3 (0.48) | ALDH1A1HPGDMAPTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516911-A | Fluorescent intracellular calcium indicators | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-05-14 | — | — | US | disclosed |