Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948078 | 0.91 | HTR2A (0.55) | TMEM97SIGMAR1CNR2 | |
| SCHEMBL8947898 | 0.90 | HTR2A (0.55) | SIGMAR1CNR2 | |
| SCHEMBL8947902 | 0.90 | KCNH2 (0.53) | TMEM97SIGMAR1CNR2 | |
| SCHEMBL8947787 | 0.89 | SIGMAR1 (0.58) | TMEM97SIGMAR1 | |
| SCHEMBL8947963 | 0.87 | SIGMAR1 (0.50) | TMEM97SIGMAR1CNR2 | |
| SCHEMBL8947881 | 0.86 | SIGMAR1 (0.55) | TMEM97SIGMAR1CNR2 | |
| SCHEMBL8947935 | 0.85 | HTR2A (0.59) | TMEM97HTR1ASIGMAR1 | |
| SCHEMBL8947762 | 0.83 | HTR1A (0.66) | HTR1ASIGMAR1 | |
| SCHEMBL8948106 | 0.82 | HTR2A (0.49) | HTR1ASIGMAR1CNR2 | |
| SCHEMBL8947985 | 0.81 | KDM4E (0.58) | HTR1ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534517-A | (Aryl(alkyl)carbonyl)-heterocyclic compounds and their use in the treatment of anxiety and depression | ADIR ET COMPAGNIE (FR) | 1996-07-09 | — | — | US | disclosed |
| US-5387586-A | Analgesics, nervous system disorders | ADIR ET COMPAGNIE (FR) | 1995-02-07 | — | — | US | disclosed |
| EP-0613898-A1 | Aryl or arylalkyl-carbonyl heterocyclic derivatives, processes for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-09-07 | — | — | EP | disclosed |