Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.65 |
| ▸ | HTR2C | P28335 | 5/20 | 0.65 |
| ▸ | HTR7 | P34969 | 4/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947933 | 0.95 | HTR1A (0.66) | HTR1AHTR2CHTR7HTR2A | |
| SCHEMBL8948014 | 0.90 | HTR1A (0.52) | HTR1AHTR2CHTR7 | |
| SCHEMBL8948011 | 0.88 | HTR1A (0.60) | HTR1AHTR2CHTR7HTR2A | |
| SCHEMBL8948013 | 0.88 | HTR1A (0.56) | HTR1AHTR2CHTR7HTR2A | |
| SCHEMBL8948074 | 0.86 | HTR1A (0.53) | HTR1AHTR2CHTR7HTR2A | |
| SCHEMBL8948000 | 0.85 | HTR2A (0.50) | HTR1AHTR2CHTR7HTR2AGRM2 | |
| SCHEMBL7765360 | 0.85 | HTR2A (0.47) | HTR1AHTR2CHTR7HTR2A | |
| SCHEMBL8947974 | 0.84 | SIGMAR1 (0.64) | HTR2CHTR7HTR2A | |
| SCHEMBL8947935 | 0.83 | HTR2A (0.59) | HTR1AHTR2CHTR7HTR2A | |
| SCHEMBL8947994 | 0.83 | CYP1A2 (0.51) | HTR1AHTR2CHTR7HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534517-A | (Aryl(alkyl)carbonyl)-heterocyclic compounds and their use in the treatment of anxiety and depression | ADIR ET COMPAGNIE (FR) | 1996-07-09 | — | — | US | disclosed |
| US-5387586-A | Analgesics, nervous system disorders | ADIR ET COMPAGNIE (FR) | 1995-02-07 | — | — | US | disclosed |
| EP-0613898-A1 | Aryl or arylalkyl-carbonyl heterocyclic derivatives, processes for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-09-07 | — | — | EP | disclosed |