Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13124953 | 1.00 | GPR84 (0.41) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL4353419 | 1.00 | GPR84 (0.41) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL13124944 | 0.98 | AKR1B1 (0.39) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL3254927 | 0.85 | FFAR3 (0.32) | TSHRKMT2A | |
| SCHEMBL30143360 | 0.84 | MEN1 (0.37) | MEN1KMT2A | |
| SCHEMBL23281437 | 0.82 | FOLH1 (0.38) | HDAC11 | |
| SCHEMBL25428919 | 0.82 | ALDH1A1 (0.39) | TSHRALDH1A1 | |
| SCHEMBL24813450 | 0.82 | LMNA (0.41) | HDAC11TSHRALDH1A1MEN1ALOX15 | |
| SCHEMBL14169233 | 0.81 | POLB (0.38) | — | |
| SCHEMBL14779365 | 0.80 | TSHR (0.40) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519128-A | Process for the synthesis of acylated derivatives of fatty acid-transporting thiols and in particular acyl-coenzymes A and the thus obtained acyl-coenzymes A | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1996-05-21 | — | — | US | disclosed |
| US-5424415-A | Process for the synthesis of acylated derivatives of fatty acid-transporting thiols and in particular acyl-coenzymes A and the thus obtained acyl-coenzymes A | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1995-06-13 | — | — | US | disclosed |