Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13124953 | 1.00 | GPR84 (0.41) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL8948233 | 1.00 | GPR84 (0.41) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL13124944 | 0.98 | AKR1B1 (0.39) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL3254927 | 0.85 | FFAR3 (0.32) | TSHRKMT2A | |
| SCHEMBL30143360 | 0.84 | MEN1 (0.37) | MEN1KMT2A | |
| SCHEMBL23281437 | 0.82 | FOLH1 (0.38) | HDAC11 | |
| SCHEMBL25428919 | 0.82 | ALDH1A1 (0.39) | TSHRALDH1A1 | |
| SCHEMBL24813450 | 0.82 | LMNA (0.41) | HDAC11TSHRALDH1A1MEN1ALOX15 | |
| SCHEMBL14169233 | 0.81 | POLB (0.38) | — | |
| SCHEMBL14779365 | 0.80 | TSHR (0.40) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191746-B | Hydroxypyridones compound and preparation method and application thereof | 暨南大学 | 2020-06-16 | — | — | CN | claimed |
| US-20220411397-A1 | ANALOGUES OF N-ACYL-HOMOSERINE LACTONES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | ECOLE NORMALE SUPERIEURE (FR) | 2022-12-29 | — | — | US | disclosed |
| US-20220411397-A1 | ANALOGUES OF N-ACYL-HOMOSERINE LACTONES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | ECOLE NORMALE SUPERIEURE (FR) | 2022-12-29 | — | — | US | disclosed |
| CN-115209891-A | Analogs of N-acyl-homoserine lactones and pharmaceutical compositions containing the same | 索邦大学 | 2022-10-18 | — | — | CN | disclosed |
| EP-4048258-A1 | ANALOGUES OF N-ACYL-HOMOSERINE LACTONES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | SORBONNE UNIVERSITE (FR) | 2022-08-31 | — | — | EP | disclosed |
| WO-2021078952-A1 | ANALOGUES OF N-ACYL-HOMOSERINE LACTONES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | SORBONNE UNIVERSITE (FR) | 2021-04-29 | — | — | WO | disclosed |
| CN-108191746-B | Hydroxypyridones compound and preparation method and application thereof | 暨南大学 | 2020-06-16 | — | — | CN | disclosed |
| US-8436210-B2 | Amide compound and bacterial disease control agent for agricultural and horticultural use | THE UNIVERSITY OF TOKYO (JP) | 2013-05-07 | — | — | US | disclosed |
| US-20100261920-A1 | AMIDE COMPOUND AND BACTERIAL DISEASE CONTROL AGENT FOR AGRICULTURAL AND HORTICULTURAL USE | THE UNIVERSITY OF TOKYO (JP) | 2010-10-14 | — | — | US | disclosed |
| US-20100261920-A1 | AMIDE COMPOUND AND BACTERIAL DISEASE CONTROL AGENT FOR AGRICULTURAL AND HORTICULTURAL USE | THE UNIVERSITY OF TOKYO (JP) | 2010-10-14 | — | — | US | disclosed |
| EP-2077109-A1 | AMIDE COMPOUND, SALT THEREOF, AND BIOFILM REMOVER USING THEM | The University of Tokyo (JP) | 2009-07-08 | — | — | EP | disclosed |
| US-7498292-B2 | Combinatorial libraries of autoinducer analogs, autoinducer agonists and antagonists, and methods of use thereof | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2009-03-03 | — | — | US | disclosed |
| US-20080241081-A1 | AMIDE COMPOUND OR SALT THEREOF, AND BIOFILM REMOVER CONTAINING THE SAME | UNIVERSITY OF TOKYO (JP) | 2008-10-02 | — | — | US | disclosed |
| US-20080241081-A1 | AMIDE COMPOUND OR SALT THEREOF, AND BIOFILM REMOVER CONTAINING THE SAME | UNIVERSITY OF TOKYO (JP) | 2008-10-02 | — | — | US | disclosed |
| US-20080027115-A1 | COMBINATORIAL LIBRARIES OF AUTOINDUCER ANALOGS, AUTOINDUCER AGONISTS AND ANTAGONISTS, AND METHODS OF USE THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-01-31 | — | — | US | disclosed |
| CN-1839204-A | Combinatorial libraries of autoinducer analogs, autoinducer agonists and antagonists, and methods of use thereof | UNIV NEW YORK (US) | 2006-09-27 | — | — | CN | disclosed |
| EP-1578359-A2 | COMBINATORIAL LIBRARIES OF AUTOINDUCER ANALOGS, AUTOINDUCER AGONISTS AND ANTAGONISTS, AND METHODS OF USE THEREOF | The Research Foundation of the State University of New York (US) | 2005-09-28 | — | — | EP | disclosed |
| US-20040115732-A1 | Combinatorial libraries of autoinducer analogs, autoinducer agonists and antagonists, and methods of use thereof | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | 2004-06-17 | — | — | US | disclosed |
| WO-2004016213-A2 | COMBINATORIAL LIBRARIES OF AUTOINDUCER ANALOGS, AUTOINDUCER AGONISTS AND ANTAGONISTS, AND METHODS OF USE THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2004-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080241081-A1 | AMIDE COMPOUND OR SALT THEREOF, AND BIOFILM REMOVER CONTAINING THE SAME | H1-0, H1-10, H1-4 | GPR84 2722/4885PPARG 3936/4885PPARD 3800/4885 |
| US-20080027115-A1 | COMBINATORIAL LIBRARIES OF AUTOINDUCER ANALOGS, AUTOINDUCER AGONISTS AND ANTAGONISTS, AND METHODS OF USE THEREOF | QRFPR, CASR, BLVRB | GPR84 110/4885PPARG 2852/4885PPARD 2324/4885 |
| US-20100261920-A1 | AMIDE COMPOUND AND BACTERIAL DISEASE CONTROL AGENT FOR AGRICULTURAL AND HORTICULTURAL USE | BROX, NAAA, H1-2 | GPR84 1224/4885PPARG 3077/4885PPARD 4371/4885 |
| US-20220411397-A1 | ANALOGUES OF N-ACYL-HOMOSERINE LACTONES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | AHCYL1, LTC4S, AHCY | GPR84 507/4885PPARG 1104/4885PPARD 945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.