Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948006 | 0.85 | L3MBTL1 (0.61) | HTTNPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8948151 | 0.80 | HTR1A (0.48) | HTTNPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8948338 | 0.73 | HTR1A (0.54) | SIGMAR1HTR1A | |
| SCHEMBL9616604 | 0.69 | L3MBTL1 (0.54) | HTTNPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL318427 | 0.69 | L3MBTL1 (0.68) | NPC1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL318582 | 0.69 | L3MBTL1 (0.64) | HTTNPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4230610 | 0.69 | L3MBTL1 (0.65) | HTTNPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4617266 | 0.69 | CYP3A4 (0.64) | NPC1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2148992 | 0.68 | CYP3A4 (0.67) | NPC1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7440654 | 0.67 | L3MBTL1 (0.73) | HTTNPC1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512569-A | SIGMA RECEPTOR DISORDERS; PSYCHOLOGICAL DISORDERS | ADIR ET COMPAGNIE (FR) | 1996-04-30 | — | — | US | disclosed |