Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948238 | 0.85 | HTT (0.48) | L3MBTL1CYP3A4CYP2D6CYP2C19RAB9A | |
| SCHEMBL8948151 | 0.82 | HTR1A (0.48) | L3MBTL1CYP3A4CYP2D6CYP2C19RAB9A | |
| SCHEMBL4616208 | 0.77 | L3MBTL1 (0.77) | L3MBTL1CYP3A4CYP2D6CYP2C19TDP1 | |
| SCHEMBL4617266 | 0.74 | CYP3A4 (0.64) | L3MBTL1CYP3A4CYP2D6CYP2C19TDP1 | |
| SCHEMBL6419192 | 0.73 | CYP3A4 (0.62) | L3MBTL1CYP3A4CYP2D6CYP2C19TDP1 | |
| SCHEMBL13985121 | 0.72 | ACHE (0.72) | — | |
| SCHEMBL8948181 | 0.72 | SIGMAR1 (0.51) | TP53SIGMAR1 | |
| SCHEMBL4616279 | 0.72 | NPC1 (0.61) | L3MBTL1CYP3A4CYP2D6CYP2C19RAB9A | |
| SCHEMBL9616604 | 0.72 | L3MBTL1 (0.54) | L3MBTL1CYP3A4CYP2D6CYP2C19RAB9A | |
| SCHEMBL318427 | 0.71 | L3MBTL1 (0.68) | L3MBTL1CYP3A4CYP2D6CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512569-A | SIGMA RECEPTOR DISORDERS; PSYCHOLOGICAL DISORDERS | ADIR ET COMPAGNIE (FR) | 1996-04-30 | — | — | US | disclosed |