Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5458653 | 0.81 | LMNA (0.64) | LMNAHPGDMAPTALDH1A1HTT | |
| SCHEMBL5297733 | 0.80 | LMNA (0.47) | LMNAHPGDMAPTALDH1A1HTT | |
| SCHEMBL10481234 | 0.79 | LMNA (0.58) | LMNAHPGDMAPTALDH1A1HTT | |
| SCHEMBL8948312 | 0.76 | MAPK9 (0.46) | LMNAHPGDMAPTALDH1A1MAPK1 | |
| SCHEMBL28630641 | 0.76 | APP (0.48) | HPGDMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL18388882 | 0.74 | ALDH1A1 (0.39) | HPGDMAPTALDH1A1HTTNPC1 | |
| SCHEMBL785194 | 0.74 | LMNA (0.56) | LMNAHPGDMAPTALDH1A1HTT | |
| SCHEMBL21721813 | 0.73 | ALDH1A1 (0.54) | HPGDMAPTALDH1A1HTTMITF | |
| SCHEMBL21686042 | 0.73 | MAPT (0.52) | LMNAHPGDMAPTALDH1A1NPC1 | |
| SCHEMBL23339899 | 0.72 | CYP2D6 (0.39) | HPGDMAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4865617-A | Dyeing compositions for keratinous fibres, especially for human hair, containing oxidation dye precursors and heterocyclic couplers | L'OREAL (FR) | 1989-09-12 | — | — | US | claimed |
| US-5542952-A | DEVELOPERS THAT FORM STABLE OXIDATION HAIR DYES | L'OREAL (FR) | 1996-08-06 | — | — | US | disclosed |
| US-5032137-A | Hair dye | L'OREAL (FR) | 1991-07-16 | — | — | US | disclosed |
| US-4979961-A | p-phenylenediamines, process for preparation thereof, dyeing composition containing them and corresponding dyeing process | L'OREAL (FR) | 1990-12-25 | — | — | US | disclosed |
| US-4865617-A | Dyeing compositions for keratinous fibres, especially for human hair, containing oxidation dye precursors and heterocyclic couplers | L'OREAL (FR) | 1989-09-12 | — | — | US | disclosed |