Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7807418 | 0.80 | MAPT (0.41) | MAPK9POLBKMT2AMEN1MAPT | |
| SCHEMBL454595 | 0.79 | TNF (0.44) | POLBLMNAALDH1A1KDM4ETDP1 | |
| SCHEMBL2326696 | 0.77 | BMPR1B (0.41) | MAPK9POLBLMNAALDH1A1KMT2A | |
| SCHEMBL8948290 | 0.76 | LMNA (0.51) | HPGDLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL21721813 | 0.75 | ALDH1A1 (0.54) | POLBHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL5458653 | 0.73 | LMNA (0.64) | POLBHPGDLMNACYP3A4ALDH1A1 | |
| SCHEMBL7809580 | 0.73 | LMNA (0.35) | MAPK9POLBHPGDLMNAALDH1A1 | |
| SCHEMBL5297733 | 0.72 | LMNA (0.47) | HPGDLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL28409276 | 0.72 | RAD52 (0.55) | POLBLMNACYP3A4ALDH1A1KMT2A | |
| SCHEMBL3971880 | 0.72 | HMGCR (0.44) | HPGDCYP3A4ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4865617-A | Dyeing compositions for keratinous fibres, especially for human hair, containing oxidation dye precursors and heterocyclic couplers | L'OREAL (FR) | 1989-09-12 | — | — | US | claimed |
| US-5542952-A | DEVELOPERS THAT FORM STABLE OXIDATION HAIR DYES | L'OREAL (FR) | 1996-08-06 | — | — | US | disclosed |
| US-5032137-A | Hair dye | L'OREAL (FR) | 1991-07-16 | — | — | US | disclosed |
| US-4979961-A | p-phenylenediamines, process for preparation thereof, dyeing composition containing them and corresponding dyeing process | L'OREAL (FR) | 1990-12-25 | — | — | US | disclosed |
| US-4865617-A | Dyeing compositions for keratinous fibres, especially for human hair, containing oxidation dye precursors and heterocyclic couplers | L'OREAL (FR) | 1989-09-12 | — | — | US | disclosed |