SCHEMBL8948376

SCHEMBL8948376

CCNCCN(CC)c1ccc(N)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.62
MAPK1 P28482 3/20 0.62
CYP3A4 P08684 3/20 0.62
TDP1 Q9NUW8 3/20 0.62
TSHR P16473 3/20 0.62
L3MBTL1 Q9Y468 2/20 0.62
PSMD14 O00487 1/20 0.62
RECQL P46063 1/20 0.62
GFER P55789 1/20 0.62
ALDH3A1 P30838 1/20 0.40
ALDH1A3 P47895 1/20 0.40
ESRRG P62508 1/20 0.40
TP53 P04637 1/20 0.38
ALOX15 P16050 1/20 0.38
LMNA P02545 3/20 0.37
CYP2C19 P33261 2/20 0.37
SLC22A2 O15244 1/20 0.37
SLC22A1 O15245 1/20 0.37
ACHE P22303 1/20 0.37
S100B P04271 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6389517 0.87 ALDH1A1 (0.55) ALDH1A1MAPK1CYP3A4TDP1TSHR
SCHEMBL18404001 0.84 ALDH1A1 (0.64) ALDH1A1MAPK1CYP3A4TDP1TSHR
SCHEMBL24393992 0.83 CNR2 (0.42) ALDH1A1MAPK1CYP3A4TDP1TSHR
SCHEMBL29740663 0.82 ALDH1A1 (0.82) ALDH1A1MAPK1CYP3A4TDP1TSHR
SCHEMBL16173977 0.81 TSHR (0.50) ALDH1A1TSHRGFERLMNAACHE
SCHEMBL27560802 0.79 ALDH1A1 (0.55) ALDH1A1MAPK1CYP3A4TDP1TSHR
SCHEMBL7520164 0.79 ALDH1A1 (0.75) ALDH1A1MAPK1CYP3A4TDP1TSHR
SCHEMBL8467252 0.78 ALDH1A1 (1.00) ALDH1A1MAPK1CYP3A4TDP1TSHR
SCHEMBL33781 0.78 ALDH1A1 (1.00) ALDH1A1MAPK1CYP3A4TDP1TSHR
SCHEMBL6389743 0.77 ALDH1A1 (0.72) ALDH1A1MAPK1CYP3A4TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5567421-A COLORFAST, WASHFAST, WEATHERPROOF, AND PERSPIRATION RESISTANT HAIR DYE L'OREAL (FR) 1996-10-22 US disclosed