Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9445170 | 0.98 | ALDH1A1 (0.41) | ALDH1A1CYP3A4TSHRTDP1MCL1 | |
| Hydrochloric Acid SCHEMBL9445172 | 0.93 | ALDH1A1 (0.41) | ALDH1A1CYP3A4TSHRTDP1MCL1 | |
| SCHEMBL12156965 | 0.76 | TDP1 (0.42) | ALDH1A1CYP3A4TDP1TP53 | |
| Hydrochloric Acid SCHEMBL8497331 | 0.76 | ALDH1A1 (0.33) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL239363 | 0.76 | CYP3A4 (0.40) | CYP3A4TSHRTP53 | |
| Hydrochloric Acid SCHEMBL9803396 | 0.75 | MAPT (0.41) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| Hydrochloric Acid SCHEMBL10636134 | 0.74 | CYP3A4 (0.39) | CYP3A4TSHRTP53 | |
| Hydrochloric Acid SCHEMBL10636139 | 0.74 | CYP3A4 (0.39) | CYP3A4TSHRTP53 | |
| Hydrochloric Acid SCHEMBL9859685 | 0.74 | MAPT (0.40) | ALDH1A1CYP3A4TSHRTDP1TP53 | |
| SCHEMBL16201864 | 0.73 | CYP3A4 (0.41) | CYP3A4TSHRHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541035-A | PHOTOSENSITIVE SHEETS FOR IMAGES AND FOR TRANSFERRING IMAGES TO SUPPORTS | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1996-07-30 | — | — | US | disclosed |
| US-5057394-A | Forming photosensitivze layer on substrate, exposing to active rays, immersing in water to allow swelling and removal | SANYO-KOKUSAKU PULP CO., LTD. (JP) | 1991-10-15 | — | — | US | disclosed |