Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 9/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 9/20 | 0.47 |
| ▸ | F10 | P00742 | 9/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948623 | 0.88 | SIGMAR1 (0.48) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL8316698 | 0.88 | ITGB3 (0.43) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL8313822 | 0.86 | ITGB3 (0.54) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL8948804 | 0.85 | SIGMAR1 (0.46) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL8948666 | 0.83 | GRM2 (0.49) | ITGB3ITGA2BSIGMAR1 | |
| SCHEMBL8948671 | 0.83 | GRM2 (0.49) | ITGB3ITGA2BSIGMAR1 | |
| SCHEMBL8948655 | 0.82 | SIGMAR1 (0.44) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL8313827 | 0.81 | ITGB3 (0.45) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL8948761 | 0.77 | ITGB3 (0.72) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL8948798 | 0.77 | ITGB3 (0.72) | ITGB3ITGA2BPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1052231-C | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 2000-05-10 | — | — | CN | disclosed |
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |
| CN-1097421-A | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 1995-01-18 | — | — | CN | disclosed |