Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948579 | 0.74 | ADORA2A (0.40) | CES1ADORA2AMAPTMEN1NPC1 | |
| SCHEMBL8948553 | 0.72 | HTR6 (0.33) | ALDH1A1 | |
| SCHEMBL8948586 | 0.71 | TYMS (0.40) | ADORA2AMAPTMEN1ALDH1A1POLB | |
| SCHEMBL659806 | 0.69 | ESR1 (0.42) | ALDH1A1POLBRECQLTDP1 | |
| SCHEMBL13742725 | 0.66 | CA1 (0.42) | MEN1ALDH1A1POLBKMT2AL3MBTL1 | |
| SCHEMBL5080247 | 0.64 | CA1 (0.42) | MAPTMEN1ALDH1A1POLBTHRB | |
| SCHEMBL8652048 | 0.64 | TYMS (0.40) | MAPTALDH1A1TDP1 | |
| SCHEMBL29922025 | 0.64 | ALDH1A1 (0.37) | MAPTMEN1NPC1ALDH1A1POLB | |
| SCHEMBL658119 | 0.63 | ESR1 (0.33) | — | |
| SCHEMBL8390696 | 0.63 | PKM (0.39) | MAPTALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521147-A | HERBICIDES | FMC CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |
| WO-1995005079-A1 | 3-(BENZOFURAN-7-YL)-6-HALOALKYLURACILS | FMC CORPORATION (US) | 1995-02-23 | — | — | WO | disclosed |