SCHEMBL8948598

SCHEMBL8948598

O=C=Nc1c(F)cc(Cl)c2c1OCCC2

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 2/20 0.32
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6825105 0.89 PDE4A (0.32) PDE4A
SCHEMBL9222418 0.81 NPC1 (0.33) MAPK1TDP1
SCHEMBL8948929 0.75 PDE4D (0.32)
SCHEMBL8948549 0.73 ACHE (0.38)
SCHEMBL6823743 0.67 ACHE (0.38)
SCHEMBL9223720 0.67 GABRA1 (0.31) MAPK1TDP1
SCHEMBL6964625 0.64 GABRA1 (0.38) MAPK1TDP1
SCHEMBL18007538 0.64 PARP1 (0.32)
SCHEMBL1952585 0.63 MAPK1 (0.38) MAPK1TDP1
SCHEMBL9835832 0.63 MAPK1 (0.38) MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5521147-A HERBICIDES FMC CORPORATION (US) 1996-05-28 US disclosed