SCHEMBL8948929

SCHEMBL8948929

CC1(C)CCc2c(Cl)cc(F)c(N=C=O)c2O1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDE4D Q08499 1/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
NFE2L2 Q16236 1/20 0.31
PKM P14618 1/20 0.31
PKLR P30613 1/20 0.31
GRM2 Q14416 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9223720 0.75 GABRA1 (0.31)
SCHEMBL8948707 0.75 GRM2 (0.34) PDE4DLMNAHPGDNFE2L2GRM2
SCHEMBL8948598 0.75 PDE4A (0.32)
SCHEMBL8948568 0.70 PDE4D (0.34) PDE4DLMNAHPGD
SCHEMBL9222418 0.69 NPC1 (0.33)
SCHEMBL6825105 0.67 PDE4A (0.32)
SCHEMBL8116746 0.64 ALDH1A1 (0.36) LMNA
SCHEMBL6964625 0.61 GABRA1 (0.38)
SCHEMBL1952585 0.61 MAPK1 (0.38)
SCHEMBL9835832 0.61 MAPK1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5521147-A HERBICIDES FMC CORPORATION (US) 1996-05-28 US disclosed