Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11446990 | 0.88 | SIGMAR1 (0.52) | SIGMAR1 | |
| SCHEMBL8948820 | 0.85 | ALDH1A1 (0.58) | ALDH1A1SIGMAR1 | |
| SCHEMBL8948610 | 0.84 | SIGMAR1 (0.55) | SIGMAR1 | |
| SCHEMBL10642802 | 0.82 | FUCA1 (0.65) | S1PR5S1PR1FUCA1GRIN2BALDH1A1 | |
| SCHEMBL11446837 | 0.76 | AGTR2 (0.47) | ALDH1A1SMN1; SMN2SIGMAR1 | |
| SCHEMBL1188233 | 0.75 | S1PR5 (0.65) | S1PR5S1PR1FUCA1GRIN2BALDH1A1 | |
| SCHEMBL1188230 | 0.75 | S1PR5 (0.65) | S1PR5S1PR1FUCA1GRIN2BALDH1A1 | |
| SCHEMBL565212 | 0.75 | S1PR5 (0.87) | S1PR5S1PR1FUCA1 | |
| SCHEMBL6231248 | 0.75 | S1PR5 (0.65) | S1PR5S1PR1FUCA1GRIN2BALDH1A1 | |
| SCHEMBL16544830 | 0.75 | FUCA1 (0.55) | S1PR5S1PR1FUCA1SIGMAR1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |