Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948784 | 0.90 | GRM2 (0.53) | F10GRM2ITGB3ITGA2BPRSS1 | |
| SCHEMBL8948675 | 0.90 | GRM2 (0.53) | F10GRM2ITGB3ITGA2BPRSS1 | |
| SCHEMBL8948634 | 0.88 | GRM2 (0.47) | F10GRM2 | |
| SCHEMBL8948686 | 0.88 | L3MBTL1 (0.47) | F10GRM2ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8948743 | 0.87 | GRM2 (0.50) | F10GRM2ITGB3ITGA2BPRSS1 | |
| SCHEMBL8446291 | 0.86 | GRM2 (0.48) | F10GRM2ITGB3ITGA2BPRSS1 | |
| SCHEMBL8948753 | 0.84 | GRM2 (0.51) | F10GRM2ITGB3ITGA2BPRSS1 | |
| SCHEMBL8948657 | 0.84 | GRM2 (0.47) | F10GRM2ITGB3ITGA2BPRSS1 | |
| SCHEMBL8948697 | 0.84 | GRM2 (0.50) | F10GRM2ITGB3ITGA2BPRSS1 | |
| SCHEMBL8948802 | 0.82 | F10 (0.51) | F10GRM2ALDH1A1KDM4EITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |