Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948720 | 0.91 | L3MBTL1 (0.49) | L3MBTL1GRM2HPGDSIGMAR1F10 | |
| SCHEMBL8948663 | 0.91 | L3MBTL1 (0.49) | L3MBTL1GRM2HPGDSIGMAR1F10 | |
| SCHEMBL8948589 | 0.91 | L3MBTL1 (0.49) | L3MBTL1GRM2HPGDSIGMAR1F10 | |
| SCHEMBL8948682 | 0.88 | F10 (0.52) | L3MBTL1GRM2F10ALDH1A1SMN1; SMN2 | |
| SCHEMBL8948592 | 0.87 | GRM2 (0.42) | L3MBTL1GRM2SIGMAR1 | |
| SCHEMBL8450620 | 0.87 | GRM2 (0.42) | L3MBTL1GRM2SIGMAR1 | |
| SCHEMBL8948743 | 0.86 | GRM2 (0.50) | GRM2SIGMAR1F10 | |
| SCHEMBL8948620 | 0.85 | L3MBTL1 (0.44) | L3MBTL1GRM2HPGDSIGMAR1 | |
| SCHEMBL8948542 | 0.85 | SIGMAR1 (0.41) | L3MBTL1GRM2SIGMAR1 | |
| SCHEMBL8948634 | 0.83 | GRM2 (0.47) | GRM2SIGMAR1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |