SCHEMBL20224979

SCHEMBL20224979

O=C(CCCC1CCCNC1)OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.56
CHRNB2 P17787 3/20 0.50
CHRNA4 P43681 3/20 0.50
CHRNB4 P30926 2/20 0.50
CHRNA3 P32297 2/20 0.50
ACP1 P24666 3/20 0.47
BRD4 O60885 2/20 0.42
PRSS1 P07477 1/20 0.42
TPSAB1 Q15661 1/20 0.42
TPSD1 Q9BZJ3 1/20 0.42
TPSG1 Q9NRR2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPK1 P28482 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
GLA P06280 1/20 0.42
KLK7 P49862 1/20 0.42
ROCK2 O75116 1/20 0.42
OPRM1 P35372 1/20 0.42
OPRD1 P41143 1/20 0.42
OPRK1 P41145 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22526968 0.87 HTR2C (0.50) KMT2AALDH1A1MAPK1L3MBTL1GLA
SCHEMBL8948696 0.85 KMT2A (0.51) KMT2ACHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL8557142 0.85 ITGB3 (0.53) ALDH1A1MAPK1L3MBTL1GLAEPHX2
SCHEMBL15358250 0.80 KMT2A (0.52) KMT2ACHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL3357350 0.79 KMT2A (0.50) KMT2ACHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL3357344 0.79 KMT2A (0.50) KMT2ACHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL24988336 0.79 CHRNB2 (0.58) KMT2ACHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL9265342 0.77 KLK7 (0.60) KMT2AALDH1A1MAPK1L3MBTL1KLK7
SCHEMBL7495579 0.77 KLK7 (0.57) KMT2AALDH1A1MAPK1L3MBTL1KLK7
SCHEMBL22525497 0.77 ALDH1A1 (0.46) KMT2AALDH1A1MAPK1L3MBTL1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180154332-A1 HIGH PURITY CHROMATOGRAPHIC MATERIALS COMPRISING ION PAIRED-BONDED PHASES FOR SUPERCRITICAL FLUID CHROMATOGRAPHY WATERS TECHNOLOGIES CORPORATION 2018-06-07 US disclosed