SCHEMBL8948707

SCHEMBL8948707

CC1(C)CCc2c(Cl)cc(F)c(N)c2O1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 2/20 0.34
PDE4D Q08499 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
CCR5 P51681 1/20 0.30
MALT1 Q9UDY8 1/20 0.30
NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8948747 0.84 HTR2A (0.33)
SCHEMBL8948929 0.75 PDE4D (0.32) GRM2PDE4DLMNAHPGDNFE2L2
SCHEMBL8948549 0.73 ACHE (0.38)
SCHEMBL9218811 0.70 CA1 (0.33)
SCHEMBL8948819 0.70 HTR1D (0.34) GRM2LMNAHPGDMALT1
SCHEMBL8500114 0.69 HTR4 (0.40) PDE4DCCR5
SCHEMBL8299325 0.66 MAPT (0.39)
SCHEMBL8948504 0.65 PDE4D (0.36) PDE4DLMNAHPGD
SCHEMBL13592377 0.64 PTGS1 (0.41) PDE4DLMNAHPGDCCR5NFE2L2
SCHEMBL30888679 0.64 AKT1 (0.32) MALT1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5521147-A HERBICIDES FMC CORPORATION (US) 1996-05-28 US disclosed