Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 7/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | HRH2 | P25021 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8449438 | 1.00 | SIGMAR1 (0.45) | SIGMAR1GRM2L3MBTL1ITGB3ITGA2B | |
| SCHEMBL8453538 | 1.00 | SIGMAR1 (0.45) | SIGMAR1GRM2L3MBTL1ITGB3ITGA2B | |
| SCHEMBL8948780 | 0.91 | ITGB3 (0.51) | SIGMAR1GRM2L3MBTL1ITGB3ITGA2B | |
| SCHEMBL8455801 | 0.87 | ITGB3 (0.54) | SIGMAR1GRM2ITGB3ITGA2BHRH1 | |
| SCHEMBL8948773 | 0.87 | SIGMAR1 (0.44) | SIGMAR1GRM2L3MBTL1ITGB3ITGA2B | |
| SCHEMBL8948876 | 0.85 | SIGMAR1 (0.43) | SIGMAR1GRM2L3MBTL1ITGB3ITGA2B | |
| SCHEMBL8453773 | 0.85 | GRM2 (0.51) | SIGMAR1GRM2ITGB3ITGA2B | |
| SCHEMBL8948726 | 0.85 | GRM2 (0.52) | SIGMAR1GRM2ITGB3ITGA2B | |
| SCHEMBL8948663 | 0.85 | L3MBTL1 (0.49) | SIGMAR1GRM2L3MBTL1ITGB3ITGA2B | |
| SCHEMBL8948589 | 0.85 | L3MBTL1 (0.49) | SIGMAR1GRM2L3MBTL1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |