Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | ABAT | P80404 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948585 | 0.83 | NLRP3 (0.47) | LMNATSHRMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11700573 | 0.79 | LMNA (0.58) | LMNATSHRMAPK1SMN1; SMN2APEX1 | |
| SCHEMBL11347525 | 0.72 | LMNA (0.51) | LMNASMN1; SMN2APEX1 | |
| SCHEMBL8727104 | 0.72 | TSHR (0.47) | LMNATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL11387512 | 0.72 | TSHR (0.47) | LMNATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL5555241 | 0.71 | LMNA (0.38) | LMNATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL8752140 | 0.71 | LMNA (0.67) | LMNATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL22645201 | 0.70 | TSHR (0.46) | LMNATSHRMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11694667 | 0.70 | APEX1 (0.43) | LMNATSHRAPEX1ALDH1A1 | |
| SCHEMBL8948559 | 0.70 | MAPK1 (0.58) | LMNATSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463080-A | 2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents | BRACCO INTERNATIONAL B.V. (NL) | 1995-10-31 | — | — | US | claimed |
| US-5569446-A | Radiohalogenation of proteins using trihalophenyl derivatives | BRACCO INTERNATIONAL B.V. | 1996-10-29 | — | — | US | disclosed |
| US-5463080-A | 2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents | BRACCO INTERNATIONAL B.V. (NL) | 1995-10-31 | — | — | US | disclosed |