Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948857 | 0.83 | LMNA (0.46) | LMNASMN1; SMN2TSHRMAPK1ALDH1A1 | |
| SCHEMBL11020558 | 0.75 | LMNA (0.46) | NLRP3LMNATET2SMN1; SMN2RECQL | |
| SCHEMBL8948705 | 0.74 | MEN1 (0.56) | LMNACA12CA1CA2CA9 | |
| SCHEMBL4311751 | 0.72 | LMNA (0.47) | LMNASMN1; SMN2TSHRMAPK1KDM4E | |
| Hydrochloric Acid SCHEMBL1020768 | 0.71 | LMNA (0.46) | LMNASMN1; SMN2TSHRMAPK1KDM4E | |
| SCHEMBL8752140 | 0.70 | LMNA (0.67) | LMNASMN1; SMN2TSHRMAPK1KDM4E | |
| Hydrochloric Acid SCHEMBL8857261 | 0.69 | LMNA (0.45) | LMNASMN1; SMN2TSHRMAPK1ALDH1A1 | |
| SCHEMBL16412711 | 0.69 | LMNA (0.42) | LMNACA1CA2SMN1; SMN2TSHR | |
| SCHEMBL8948809 | 0.69 | TSHR (0.43) | LMNARECQLTSHRMAPK1KDM4E | |
| Hydrochloric Acid SCHEMBL8089018 | 0.69 | LMNA (0.65) | LMNASMN1; SMN2TSHRMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569446-A | Radiohalogenation of proteins using trihalophenyl derivatives | BRACCO INTERNATIONAL B.V. | 1996-10-29 | — | — | US | disclosed |
| US-5463080-A | 2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents | BRACCO INTERNATIONAL B.V. (NL) | 1995-10-31 | — | — | US | disclosed |