Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 17/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8949186 | 0.85 | JAK2 (0.36) | — | |
| Hydrochloric Acid SCHEMBL8949011 | 0.84 | ITGB3 (0.40) | — | |
| SCHEMBL9264885 | 0.82 | EGLN1 (0.35) | EGLN1KDM1A | |
| SCHEMBL8949110 | 0.80 | FASN (0.41) | FASNEGLN1KDM1A | |
| SCHEMBL8949062 | 0.80 | CCNK (0.47) | FASNEGLN1 | |
| SCHEMBL8407569 | 0.78 | CCNK (0.51) | FASNKDM1A | |
| SCHEMBL8949359 | 0.73 | ITGB3 (0.48) | — | |
| SCHEMBL8560134 | 0.72 | KDM1A (0.49) | EGLN1KDM1A | |
| SCHEMBL8718956 | 0.72 | MLNR (0.48) | KDM1A | |
| SCHEMBL7674090 | 0.71 | RAB9A (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |