Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | CRHBP | P24387 | 2/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 3/20 | 0.42 |
| ▸ | EIF4E | P06730 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949225 | 0.89 | CASP1 (0.43) | MEN1KMT2ACRHBPCRHR2EGLN1 | |
| SCHEMBL3540633 | 0.83 | MEN1 (0.62) | MEN1KMT2ACRHBPCRHR2HPGD | |
| SCHEMBL8085536 | 0.82 | MEN1 (0.63) | MEN1KMT2ACRHBPCRHR2HPGD | |
| SCHEMBL27576873 | 0.79 | MEN1 (0.53) | MEN1KMT2ACRHBPCRHR2HPGD | |
| SCHEMBL9650514 | 0.74 | SMN1; SMN2 (0.46) | MEN1KMT2ASLC22A12KDM4ENPC1 | |
| SCHEMBL9650630 | 0.73 | BRS3 (0.40) | MEN1KMT2AEGLN1SLC22A12MAP4K4 | |
| SCHEMBL9650800 | 0.72 | ALDH1A1 (0.45) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL2116125 | 0.71 | LMNA (0.43) | MEN1KMT2AHPGDALDH1A1CASP1 | |
| SCHEMBL22573742 | 0.70 | MEN1 (0.48) | MEN1KMT2ACRHBPCRHR2HPGD | |
| SCHEMBL5937360 | 0.70 | LDHA (0.65) | EGLN1SLC22A12MAP4K4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |