Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.45 |
| ▸ | PLAU | P00749 | 5/20 | 0.42 |
| ▸ | PLAT | P00750 | 5/20 | 0.42 |
| ▸ | F2 | P00734 | 9/20 | 0.42 |
| ▸ | F10 | P00742 | 8/20 | 0.42 |
| ▸ | F7 | P08709 | 6/20 | 0.42 |
| ▸ | F3 | P13726 | 6/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 3/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.41 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8949189 | 0.90 | SMN1; SMN2 (0.44) | PLAUPLATF2F10F7 | |
| SCHEMBL8949239 | 0.80 | ITGB3 (0.45) | F10ITGB3ITGA2B | |
| SCHEMBL8949063 | 0.78 | ITGB3 (0.47) | F10ITGB3ITGA2B | |
| SCHEMBL8949398 | 0.78 | ITGB3 (0.40) | F2F7F3PHGDHITGB3 | |
| SCHEMBL8949033 | 0.78 | ITGB3 (0.51) | ITGB3ITGA2B | |
| SCHEMBL8949099 | 0.78 | F10 (0.42) | PLAUPLATF2F10PHGDH | |
| SCHEMBL8949188 | 0.76 | ALDH1A1 (0.38) | F2F10PHGDHITGB3ITGA2B | |
| SCHEMBL8949128 | 0.76 | PHGDH (0.35) | F2PHGDHITGB3ITGA2BKLKB1 | |
| SCHEMBL8949139 | 0.74 | KDM5B (0.39) | F2F10PHGDHITGB3ITGA2B | |
| SCHEMBL8949288 | 0.74 | KDM4E (0.43) | NR1H4PHGDHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |