Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8949189 | 0.83 | SMN1; SMN2 (0.44) | KDM4EKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9571680 | 0.79 | EGLN1 (0.42) | KDM4ESMN1; SMN2ALDH1A1GAAHPGD | |
| SCHEMBL7275259 | 0.74 | PHGDH (0.48) | KDM4EKMT2AALDH1A1GAAHPGD | |
| SCHEMBL8949066 | 0.74 | ALDH1A1 (0.46) | KDM4ESMN1; SMN2NPC1RAB9ARXFP1 | |
| SCHEMBL8949264 | 0.74 | NR1H4 (0.45) | KDM4EPHGDHNR1H4 | |
| SCHEMBL7276252 | 0.73 | HPGD (0.57) | KDM4EKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7277714 | 0.72 | PHGDH (0.35) | KDM4EALDH1A1GAAHPGDPHGDH | |
| SCHEMBL8949190 | 0.72 | PHGDH (0.43) | KDM4EALDH1A1GAAHPGDPHGDH | |
| SCHEMBL8949262 | 0.72 | EGLN1 (0.45) | KMT2ARAB9APHGDHCNR2 | |
| SCHEMBL8949256 | 0.72 | EGLN1 (0.45) | KMT2ARAB9APHGDHCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |