Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443498 | 0.84 | TMEM97 (0.45) | TMEM97SIGMAR1SMN1; SMN2CHRM2POLB | |
| SCHEMBL8949377 | 0.81 | HTR1A (0.43) | SMN1; SMN2CHRM2LMNASCN8A | |
| SCHEMBL14416025 | 0.79 | MAOA (0.49) | SIGMAR1CHRM2TDP1MAOASCN8A | |
| SCHEMBL8949671 | 0.77 | SIGMAR1 (0.46) | TMEM97SIGMAR1SMN1; SMN2CHRM2POLB | |
| SCHEMBL8445852 | 0.76 | SMN1; SMN2 (0.42) | SIGMAR1SMN1; SMN2LMNATP53KDM4E | |
| SCHEMBL8445940 | 0.69 | CHRM2 (0.50) | TMEM97SIGMAR1SMN1; SMN2CHRM2POLB | |
| SCHEMBL9523328 | 0.68 | SIGMAR1 (0.70) | TMEM97SIGMAR1SMN1; SMN2CHRM2BCHE | |
| SCHEMBL8444335 | 0.68 | TMEM97 (0.45) | TMEM97SIGMAR1SMN1; SMN2CHRM2POLB | |
| SCHEMBL8443179 | 0.67 | ALDH1A1 (0.50) | TMEM97SIGMAR1SMN1; SMN2CHRM2POLB | |
| SCHEMBL8445814 | 0.67 | CHRM2 (0.50) | TMEM97SIGMAR1SMN1; SMN2CHRM2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547972-A | 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1996-08-20 | — | — | US | disclosed |
| WO-1995022327-A1 | USE OF 1-(ARYLALKYLAMINOALKYL) IMIDAZOLES FOR TREATING NEUROLOGICAL DAMAGE | KNOLL AG (DE) | 1995-08-24 | — | — | WO | disclosed |
| EP-0618907-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | Knoll AG (DE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993013075-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |