Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.50 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949087 | 0.96 | ITGB3 (0.55) | ITGB3ITGA2BF10MAPK1 | |
| Hydrochloric Acid SCHEMBL8949145 | 0.86 | ALDH1A1 (0.46) | ITGB3ITGA2BF10KDM4EALDH1A1 | |
| SCHEMBL8409855 | 0.86 | MAPK1 (0.62) | ITGB3ITGA2BF10MAPK1PPARG | |
| Hydrochloric Acid SCHEMBL8949026 | 0.83 | TMPRSS15 (0.45) | ITGB3ITGA2BF10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8408094 | 0.81 | MAPK1 (0.68) | ITGB3ITGA2BF10MAPK1 | |
| SCHEMBL8949326 | 0.79 | F10 (0.39) | ITGB3ITGA2BF10 | |
| SCHEMBL8407980 | 0.77 | F10 (0.60) | ITGB3ITGA2BF10MAPK1CA1 | |
| SCHEMBL8948975 | 0.76 | ITGB3 (0.50) | ITGB3ITGA2B | |
| SCHEMBL7306809 | 0.73 | ITGB3 (0.70) | ITGB3ITGA2BF10MAPK1CA1 | |
| SCHEMBL8949046 | 0.72 | ITGB3 (0.50) | ITGB3ITGA2BMAPK1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |