Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8949245 | 0.89 | TMPRSS15 (0.38) | F10NQO2PRSS1TMPRSS15CD274 | |
| SCHEMBL8949352 | 0.79 | ITGB3 (0.50) | F10ITGB3ITGA2B | |
| SCHEMBL8949087 | 0.78 | ITGB3 (0.55) | F10ITGB3ITGA2B | |
| SCHEMBL8949379 | 0.75 | HPGD (0.38) | F10NQO2ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8949145 | 0.73 | ALDH1A1 (0.46) | F10PRSS1TMPRSS15ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8949026 | 0.72 | TMPRSS15 (0.45) | F10PRSS1TMPRSS15ITGB3ITGA2B | |
| SCHEMBL8948975 | 0.68 | ITGB3 (0.50) | NQO2TMPRSS15ITGB3ITGA2B | |
| SCHEMBL14369773 | 0.68 | WDR5 (0.50) | NQO2PRSS1 | |
| SCHEMBL8886097 | 0.67 | PRSS1 (0.49) | F10PRSS1TMPRSS15ITGB3ITGA2B | |
| SCHEMBL8975393 | 0.66 | WDR5 (0.55) | NQO2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563268-A | FOR PREVENTING CELL AGGLOMERATION, TREATING THROMBOSIS, ARTERIOSCLEROSIS, BRAIN, LUNG OR CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-10-08 | — | — | US | disclosed |
| US-5418233-A | FOR INHIBITING CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1995-05-23 | — | — | US | disclosed |
| EP-0537696-A1 | Heterobiaryl derivatives, medicines containing those compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |