Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.41 |
| ▸ | SOD1 | P00441 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445965 | 0.84 | CYP26A1 (0.47) | ALDH1A1CYP19A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL8949380 | 0.82 | ALDH1A1 (0.46) | ALDH1A1CYP19A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL8444481 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAEGLN3 | |
| SCHEMBL7873815 | 0.80 | HMOX1 (0.56) | CYP19A1KMT2ATBXAS1MEN1POLB | |
| SCHEMBL8447205 | 0.78 | SOD1 (0.54) | ALDH1A1CYP19A1KMT2ASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL8446128 | 0.78 | POLB (0.45) | CYP19A1KMT2ATBXAS1SOD1MEN1 | |
| SCHEMBL7877364 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KMT2ASMN1; SMN2LMNAHTT | |
| Hydrochloric Acid SCHEMBL8446125 | 0.76 | SOD1 (0.52) | ALDH1A1CYP19A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL8445700 | 0.76 | EGLN3 (0.45) | ALDH1A1TBXAS1EGLN3 | |
| Hydrochloric Acid SCHEMBL8446129 | 0.76 | SOD1 (0.52) | ALDH1A1CYP19A1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547972-A | 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1996-08-20 | — | — | US | disclosed |
| WO-1993013075-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |
| WO-1993006092-A1 | PIPERAZINYL (SULFONYL)AMIDE DERIVATIVES OF CAMPHOR AS OXYTOCIN ANTAGONISTS | MERCK & CO., INC. (US) | 1993-04-01 | — | — | WO | disclosed |