Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445965 | 0.81 | CYP26A1 (0.47) | EGLN3TBXAS1ALDH1A1 | |
| SCHEMBL8949477 | 0.76 | ALDH1A1 (0.44) | EGLN3TBXAS1ALDH1A1 | |
| SCHEMBL8949380 | 0.76 | ALDH1A1 (0.46) | EGLN3TBXAS1ALDH1A1KDM4E | |
| SCHEMBL8444481 | 0.75 | SMN1; SMN2 (0.50) | EGLN3KDM4E | |
| SCHEMBL8443495 | 0.75 | CYP11B1 (0.49) | EGLN3TBXAS1ALDH1A1 | |
| SCHEMBL7873815 | 0.75 | HMOX1 (0.56) | TBXAS1KDM4E | |
| SCHEMBL7313601 | 0.72 | ALDH1A1 (0.67) | EGLN3TBXAS1ALDH1A1KDM4E | |
| SCHEMBL7877364 | 0.71 | ALDH1A1 (0.46) | EGLN3TBXAS1ALDH1A1KDM4ENPSR1 | |
| SCHEMBL15190312 | 0.70 | HPGD (0.69) | EGLN3 | |
| SCHEMBL10651065 | 0.70 | CYP19A1 (0.57) | EGLN3TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618907-B1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | BRITISH TECH GROUP INT (GB) | 1999-04-28 | — | — | EP | disclosed |
| US-5547972-A | 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1996-08-20 | — | — | US | disclosed |
| WO-1993013075-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |