Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 17/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949603 | 0.91 | GCGR (0.58) | GCGRMAPK10MAPK14 | |
| SCHEMBL6955874 | 0.89 | GCGR (0.61) | GCGR | |
| SCHEMBL8949995 | 0.86 | ALDH1A1 (0.46) | GCGRALDH1A1 | |
| SCHEMBL8949786 | 0.85 | GCGR (0.47) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL14097269 | 0.84 | GCGR (0.49) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL9872802 | 0.84 | GCGR (0.45) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL6953305 | 0.84 | GCGR (0.44) | GCGRALDH1A1 | |
| SCHEMBL9744972 | 0.82 | GCGR (0.47) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL8949683 | 0.79 | GCGR (0.53) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL10423715 | 0.79 | GCGR (0.43) | GCGRALDH1A1MAPK10MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502057-A | Polysubstituted pyridines useful for treating lipoproteinanaemia and arteriosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| US-5470982-A | Disubstituted pyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1995-11-28 | — | — | US | disclosed |
| EP-0325129-B1 | Disubstituted pyridines | BAYER AG (DE) | 1994-09-07 | — | — | EP | disclosed |
| US-5173495-A | 7-[(2,6-dialkyl-4-furyl or thienyl-pyridyl)]-3,5-di-(dihydroxy-6-enoates) useful for treating circulatory diseases | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-22 | — | — | US | disclosed |
| EP-0325129-A2 | Disubstituted pyridines | BAYER AG (DE) | 1989-07-26 | — | — | EP | disclosed |