SCHEMBL8950304

SCHEMBL8950304

Cc1ccc(C2C(=O)N3CCCCN3C2=O)cc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.44
MAPK1 P28482 2/20 0.44
MEN1 O00255 5/20 0.44
CHRNA7 P36544 1/20 0.43
GAA P10253 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.40
ABL1 P00519 1/20 0.40
RIN1 Q13671 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 2/20 0.38
PKM P14618 1/20 0.36
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
SLC18A3 Q16572 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8950527 0.81 ALDH1A1 (0.46) KMT2AMAPK1MEN1CHRNA7ABL1
SCHEMBL8950369 0.80 LMNA (0.43) KMT2AMAPK1MEN1GAAALDH1A1
SCHEMBL8950283 0.75 SMN1; SMN2 (0.40) KMT2AMEN1ALDH1A1MAPTRAB9A
SCHEMBL8950302 0.70 GAA (0.40) GAAALDH1A1MAPT
SCHEMBL19227946 0.69 F2 (0.63) KMT2AMEN1GAAALDH1A1RAB9A
SCHEMBL4459107 0.68 HPGD (0.31) KMT2AALDH1A1
SCHEMBL6526805 0.68 MAPK1 (0.41) KMT2AMAPK1MEN1CHRNA7GAA
SCHEMBL4916675 0.68 KMT2A (0.53) KMT2AMAPK1MEN1GAAL3MBTL1
SCHEMBL14665739 0.66 MEN1 (0.54) KMT2AMEN1GAATDP1ALDH1A1
SCHEMBL25669423 0.66 MAPK1 (0.42) KMT2AMAPK1MEN1CHRNA7GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0577629-B1 NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS CIBA GEIGY AG (CH) 1996-06-26 EP claimed
EP-0577629-A1 NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS. CIBA GEIGY AG (CH) 1994-01-12 EP claimed
WO-1992016510-A1 NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS CIBA-GEIGY AG (CH) 1992-10-01 WO claimed
EP-0577629-B1 NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS CIBA GEIGY AG (CH) 1996-06-26 EP disclosed
US-5506193-A Herbicidally, acaricidally and insecticidally active pyrazolidine compounds CIBA-GEIGY CORPORATION (US) 1996-04-09 US disclosed
US-5494890-A FOR CONTROLLING WEEDS, INSECTS, MITES CIBA-GEIGY CORPORATION (US) 1996-02-27 US disclosed
EP-0577629-A1 NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS. CIBA GEIGY AG (CH) 1994-01-12 EP disclosed
WO-1992016510-A1 NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS CIBA-GEIGY AG (CH) 1992-10-01 WO disclosed