Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | LOX | P28300 | 1/20 | 0.42 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.42 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498051 | 0.86 | ALDH1A1 (0.50) | KMT2AMEN1MAPTRAB9AGAA | |
| SCHEMBL6312665 | 0.81 | MAPT (0.56) | KMT2AMEN1MAPTRAB9AGAA | |
| SCHEMBL15131571 | 0.77 | F2 (0.55) | KMT2AMEN1MAPTRAB9AGAA | |
| SCHEMBL19227946 | 0.72 | F2 (0.63) | KMT2AMEN1RAB9AGAAALDH1A1 | |
| SCHEMBL12900984 | 0.71 | LMNA (0.50) | KMT2AMEN1MAPTRAB9AGAA | |
| SCHEMBL23295127 | 0.71 | FPR1 (0.50) | KMT2AMEN1MAPTRAB9AGAA | |
| SCHEMBL8717385 | 0.71 | MEN1 (0.56) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL10559578 | 0.68 | MEN1 (1.00) | KMT2AMEN1MAPTRAB9AGAA | |
| SCHEMBL8950304 | 0.68 | KMT2A (0.44) | KMT2AMEN1MAPTRAB9AGAA | |
| SCHEMBL30641875 | 0.68 | ALDH1A1 (1.00) | KMT2AMEN1MAPTRAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287390-A1 | Pyrazolidinol compounds | A-VIRAL AS (NO) | 2008-11-20 | — | — | US | disclosed |
| US-20070037772-A1 | Pyrazolidinol compounds | A-VIRAL AS (NO) | 2007-02-15 | — | — | US | disclosed |
| EP-1194409-B1 | PYRAZOLIDINOL COMPOUNDS | VIRAL ASA A (NO) | 2006-02-01 | — | — | EP | disclosed |
| US-6852749-B1 | Pyrazolidinol compounds | A-VIRAL AS (NO) | 2005-02-08 | — | — | US | disclosed |
| US-20040152751-A1 | Pyrazolidinol compounds | TJOTTA ENOK (NO) | 2004-08-05 | — | — | US | disclosed |
| EP-1194409-A1 | PYRAZOLIDINOL COMPOUNDS | A-Viral AS (NO) | 2002-04-10 | — | — | EP | disclosed |
| WO-2001000585-A1 | PYRAZOLIDINOL COMPOUNDS | A-VIRAL AS (NO) | 2001-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287390-A1 | Pyrazolidinol compounds | NOX5, TPMT, ICOS | KMT2A 2530/4885MEN1 4856/4885MAPT 4445/4885 |
| US-20070037772-A1 | Pyrazolidinol compounds | NOX5, TPMT, ICOS | KMT2A 2530/4885MEN1 4856/4885MAPT 4445/4885 |
| US-20040152751-A1 | Pyrazolidinol compounds | NOX5, TPMT, ICOS | KMT2A 2530/4885MEN1 4856/4885MAPT 4445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.