Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8950798 | 0.99 | HRH3 (0.34) | HRH3SMPD1SIGMAR1KCNH2SLC6A2 | |
| SCHEMBL6582164 | 0.85 | HTR2A (0.43) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL6582237 | 0.84 | HTR2A (0.42) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6577701 | 0.80 | SMPD1 (0.55) | SMPD1 | |
| SCHEMBL6579435 | 0.79 | SIGMAR1 (0.40) | HRH3SMPD1SIGMAR1KCNH2SLC6A2 | |
| Hydrochloric Acid SCHEMBL6579984 | 0.79 | SMPD1 (0.54) | SMPD1 | |
| Hydrochloric Acid SCHEMBL6579694 | 0.78 | SIGMAR1 (0.39) | HRH3SMPD1SIGMAR1KCNH2SLC6A2 | |
| SCHEMBL6582348 | 0.77 | KCNH2 (0.43) | HRH3SMPD1SIGMAR1KCNH2PTPN1 | |
| SCHEMBL6580042 | 0.77 | DRD1 (0.48) | SMPD1SIGMAR1 | |
| SCHEMBL6582761 | 0.77 | KCNH2 (0.53) | HRH3SIGMAR1KCNH2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547967-A | HYPOTENSIVE AGENT, ANTIISCHEMIC AGENT | KALI-CHEMIE PHARMA GMBH (DE) | 1996-08-20 | — | — | US | disclosed |