Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13527339 | 0.92 | MEN1 (0.40) | MEN1KMT2AMAPK1POLBHRH3 | |
| SCHEMBL3169396 | 0.89 | MEN1 (0.35) | MEN1KMT2AMAPK1POLBHPGD | |
| SCHEMBL14335874 | 0.87 | KMT2A (0.40) | MEN1KMT2AMAPK1TP53SMN1; SMN2 | |
| SCHEMBL2430037 | 0.85 | KMT2A (0.35) | MEN1KMT2APOLBHPGDSMN1; SMN2 | |
| SCHEMBL3761042 | 0.81 | LMNA (0.40) | MEN1KMT2AMAPK1TP53HPGD | |
| SCHEMBL14335890 | 0.80 | KMT2A (0.37) | MEN1KMT2AMAPK1POLBL3MBTL1 | |
| SCHEMBL1152756 | 0.80 | ALDH1A1 (0.38) | MEN1KMT2AMAPK1POLBHPGD | |
| SCHEMBL1812603 | 0.80 | SMN1; SMN2 (0.42) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL14405362 | 0.79 | MEN1 (0.36) | MEN1KMT2AMAPK1HPGDSMN1; SMN2 | |
| SCHEMBL14405324 | 0.79 | KMT2A (0.36) | MEN1KMT2AMAPK1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577629-B1 | NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS | CIBA GEIGY AG (CH) | 1996-06-26 | — | — | EP | disclosed |
| WO-1996011574-A1 | HERBICIDAL COMPOSITIONS | NOVARTIS AG (CH) | 1996-04-25 | — | — | WO | disclosed |
| US-5506193-A | Herbicidally, acaricidally and insecticidally active pyrazolidine compounds | CIBA-GEIGY CORPORATION (US) | 1996-04-09 | — | — | US | disclosed |
| US-5494890-A | FOR CONTROLLING WEEDS, INSECTS, MITES | CIBA-GEIGY CORPORATION (US) | 1996-02-27 | — | — | US | disclosed |
| WO-1992016510-A1 | NOVEL HERBICIDALLY, ACARICIDALLY AND INSECTICIDALLY ACTIVE COMPOUNDS | CIBA-GEIGY AG (CH) | 1992-10-01 | — | — | WO | disclosed |